Bağışıklık sistemi geliştirici etki
Daha önceki araştırmalarda ipek peptitin makrofajları ve proinflamatuar sitokinlerin üretimini uyardığını göstermesine rağmen doğal öldürücü (NK) hücre işlevi üzerindeki etkisi Jang ve arkadaşlarının yaptığı çalışma ile araştırılmıştır.
İpek peptitin NK hücreleri üzerindeki modülatör aktivitesini değerlendirmek için farelere 2 ay boyunca çeşitli miktarlarda ipek peptit takviyeli diyet verilerek ve NK hücre aktivasyonu dahil olmak üzere immun stimulasyon üzerindeki etkileri değerlendirilmiştir.
Çalışma sonucunda ipek peptitinin oral yoldan verilmesi, doza bağımlı bir şekilde olgun NK hücrelerinin sıklığını arttırdı ve hatta NK hücre frekansını inhibe eden yüksek doz ipek peptiti, NK hücre olgunlaşmasını önemli ölçüde arttırdığı gözlenmiştir. Kısaca açıklamak gerekirse ipek peptitin ağızdan tüketimi NK hücrelerinin doğal bağışıklık fonksiyonlarını etkilemeyi teşvik eder ve kanser hastalarında optimal NK hücre aktivitesini desteklemek için tamamlayıcı bir terapi olarak kullanılabilir.
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